Bram van Ginneken was born in Nuenen in 1970. He studied Physics at Eindhoven University of Technology and Utrecht University. In 2001, he obtained his PhD at the Image Sciences Institute on Computer-Aided Diagnosis in Chest Radiography, where he continued to work and set up a research group on medical image analysis. His PhD research on automated detection of tuberculosis resulted in medical device software called CAD4TB. With installations in over 75 countries worldwide, CAD4TB is the most widely used autonomous AI solution for the interpretation of medical images. In 2010, he moved to Radboud University Medical Center where he set up the Diagnostic Image Analysis Group and was appointed full professor in 2012. He (co-)authored over 300 publications in international journals. Since 2010, he also works for the Fraunhofer Institute for Digital Medicine MEVIS in Bremen, Germany. In 2014, he founded Thirona, a company that develops software for CT lung image analysis. He pioneered the concept of challenges in medical image analysis and created In 2024, he founded Plain Medical, a company that develops AI solutions to reduce the workload of radiologists.